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Markus Glatzel Selected Research

Familial encephalopathy with neuroserpin inclusion bodies

1/2021G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic.
2/2016Limited Unfolded Protein Response and Inflammation in Neuroserpinopathy.
10/2014Lectin OS-9 delivers mutant neuroserpin to endoplasmic reticulum associated degradation in familial encephalopathy with neuroserpin inclusion bodies.
3/2013A novel interaction between aging and ER overload in a protein conformational dementia.
4/2007Accumulation of mutant neuroserpin precedes development of clinical symptoms in familial encephalopathy with neuroserpin inclusion bodies.

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Markus Glatzel Research Topics

Disease

38Prion Diseases (Transmissible Spongiform Encephalopathies)
11/2021 - 06/2002
25Alzheimer Disease (Alzheimer's Disease)
11/2022 - 05/2006
20Neoplasms (Cancer)
12/2022 - 12/2010
15Neurodegenerative Diseases (Neurodegenerative Disease)
11/2021 - 05/2006
14Infections
01/2022 - 01/2003
9Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
06/2020 - 01/2004
7Stroke (Strokes)
08/2020 - 11/2012
6Dementia (Dementias)
01/2022 - 03/2013
6Ischemic Stroke
08/2020 - 11/2012
6Brain Neoplasms (Brain Tumor)
01/2019 - 03/2012
6Sporadic Creutzfeldt-Jakob Disease
01/2008 - 11/2003
5COVID-19
01/2022 - 09/2020
5Glioblastoma (Glioblastoma Multiforme)
01/2021 - 05/2011
5Familial encephalopathy with neuroserpin inclusion bodies
01/2021 - 04/2007
5Disease Progression
06/2020 - 11/2010
4Inflammation (Inflammations)
01/2022 - 01/2013
4Gliosis
01/2022 - 06/2012
4Amyloid Plaque
11/2021 - 01/2009
4Glioma (Gliomas)
10/2021 - 12/2010
4Multiple Sclerosis
10/2019 - 01/2006
4Scrapie
01/2018 - 09/2002
4Parkinson Disease (Parkinson's Disease)
10/2014 - 04/2007
3Fibrosis (Cirrhosis)
01/2021 - 08/2009
3Neoplasm Metastasis (Metastasis)
01/2020 - 07/2014
3Brain Diseases (Brain Disorder)
01/2019 - 06/2004
3Circulating Neoplastic Cells
01/2019 - 07/2014
3Bovine Spongiform Encephalopathy (Mad Cow Disease)
01/2019 - 06/2006
3Atrophy
12/2017 - 08/2009
3Neurofibroma
12/2015 - 08/2012
2Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
11/2022 - 01/2022
2Cognitive Dysfunction
11/2022 - 01/2020
2Adenoma (Adenomas)
02/2021 - 01/2019
2Carcinogenesis
10/2020 - 12/2018
2Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis)
01/2020 - 08/2008
2Mitochondrial Diseases (Mitochondrial Disease)
01/2020 - 04/2014
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2020 - 01/2019
2Neuroinflammatory Diseases
11/2019 - 02/2016
2Chronic Wasting Disease
01/2019 - 10/2010
2Leukemia
01/2019 - 07/2012
2Inborn Genetic Diseases (Disease, Hereditary)
01/2018 - 01/2016
2Mucolipidoses (Sialidosis)
01/2016 - 07/2010
2Hemorrhage
12/2015 - 05/2009
2Brain Injuries (Brain Injury)
11/2014 - 01/2013
2Paralysis (Palsy)
04/2014 - 03/2013
2Infarction (Infarctions)
11/2013 - 01/2013
2Tauopathies
03/2013 - 04/2007

Drug/Important Bio-Agent (IBA)

36Prion ProteinsIBA
11/2021 - 01/2003
33Proteins (Proteins, Gene)FDA Link
12/2022 - 01/2004
29PrionsIBA
11/2021 - 06/2002
15Amyloid (Amyloid Fibrils)IBA
03/2022 - 01/2008
11Biomarkers (Surrogate Marker)IBA
12/2022 - 06/2006
7Presenilin-1IBA
11/2022 - 07/2011
7Amyloid beta-PeptidesIBA
11/2022 - 01/2008
7NeuroserpinIBA
01/2021 - 04/2007
6Protein Isoforms (Isoforms)IBA
11/2019 - 01/2012
5Flavin-Adenine Dinucleotide (FAD)IBA
11/2022 - 04/2014
5AntibodiesIBA
10/2021 - 01/2003
5Peptide Hydrolases (Proteases)FDA Link
06/2020 - 06/2004
5EnzymesIBA
01/2019 - 07/2010
5Metalloproteases (Metalloproteinases)IBA
01/2018 - 08/2013
4RNA (Ribonucleic Acid)IBA
10/2022 - 09/2020
4CytokinesIBA
01/2019 - 04/2016
3DNA (Deoxyribonucleic Acid)IBA
12/2022 - 01/2019
3Peptides (Polypeptides)IBA
03/2022 - 08/2013
3Glial Fibrillary Acidic ProteinIBA
02/2021 - 07/2014
3Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
01/2021 - 01/2013
3Mannose (D-Mannose)IBA
01/2020 - 07/2010
3Polysaccharides (Glycans)IBA
01/2020 - 01/2018
3ErbB Receptors (EGF Receptor)IBA
01/2019 - 07/2013
3Interleukin-17 (Interleukin 17)IBA
01/2018 - 11/2012
2Amyloid Precursor Protein Secretases (beta-Secretase)IBA
03/2022 - 02/2016
2Tiopronin (Thiola)FDA Link
03/2022 - 02/2016
2Apolipoproteins E (ApoE)IBA
01/2022 - 01/2017
2InterferonsIBA
01/2022 - 08/2014
2Subgenomic RNAIBA
01/2022 - 01/2021
2LigandsIBA
11/2021 - 01/2018
2Retinaldehyde (Retinal)IBA
11/2021 - 05/2009
2Keratins (Keratin)IBA
02/2021 - 03/2009
2Histones (Histone)IBA
10/2020 - 12/2013
2Glucose (Dextrose)FDA LinkGeneric
08/2020 - 11/2013
2Oxygen (Dioxygen)IBA
08/2020 - 11/2013
2Protein AggregatesIBA
01/2020 - 02/2016
2Cathepsin DIBA
01/2020 - 08/2008
2CalciumIBA
01/2020 - 04/2014
2Heparitin Sulfate (Heparan Sulfate)IBA
01/2020 - 01/2020
2Protein Sorting Signals (Signal Peptide)IBA
01/2019 - 01/2014
2Epithelial Cell Adhesion MoleculeIBA
01/2019 - 01/2019
2Transcription Factors (Transcription Factor)IBA
01/2019 - 12/2018
2Glycoproteins (Glycoprotein)IBA
01/2018 - 11/2017
2Immunoglobulin G (IgG)IBA
11/2017 - 01/2009
2AntigensIBA
04/2017 - 10/2009
2ParaffinIBA
12/2015 - 01/2004
2globotriaosylceramide (globotriosylceramide)IBA
03/2015 - 06/2012
2Phosphotransferases (Kinase)IBA
04/2014 - 03/2013
2Codon (Codons)IBA
03/2014 - 06/2002
2Messenger RNA (mRNA)IBA
03/2012 - 08/2009
2Doxorubicin (Adriamycin)FDA LinkGeneric
08/2011 - 05/2011

Therapy/Procedure

14Therapeutics
10/2021 - 04/2007
2Drug Therapy (Chemotherapy)
10/2021 - 05/2011
2Transplantation
01/2010 - 08/2008